Table 5 Open reading frames in the lydicamycin biosynthetic gene cluster
orf (locus tag) | size (aa) | proposed function | BLAST search | |
|---|---|---|---|---|
protein homolog, origin, accession number | %b | |||
TPA0598_03_00650a | 473 | acyl-CoA ligase | hypothetical protein, Streptomyces sp. FxanaC1, WP_018093236 | 94/96 |
TPA0598_03_00660 | 929 | LuxR family transcriptional regulator | LuxR family transcriptional regulator, Streptomyces sp. FxanaC1, WP_026170289 | 91/94 |
TPA0598_03_00670a | 274 | unknown | hypothetical protein, Saccharomonospora azurea, EHY88948 | 53/64 |
TPA0598_03_00680 | 632 | two-component system histidine kinase | hypothetical protein, Streptomyces sp. FxanaC1, WP_018093233 | 93/95 |
TPA0598_03_00690 | 218 | two-compornent system response regulator | LuxR family transcriptional regulator, Streptomyces sp. FxanaC1, WP_018093232 | 99/99 |
TPA0598_03_00700a | 336 | transacylase | ACP S-malonyltransferase, Streptomyces sp. FxanaC1, WP_026170288 | 89/93 |
TPA0598_03_00710a | 123 | unknown | hypothetical protein, Streptomyces sp. FxanaC1, WP_018093229 | 88/95 |
TPA0598_03_00720 | 64 | unknown | hypothetical protein JCGZ_17256, Jatropha curcas, KDP45649 | 43/54 |
TPA0598_03_00730a | 80 | unknown | putative protein-disulfide isomerase, Xanthomonas gardneri, EGD16922 | 56/63 |
TPA0598_03_00740 | 3,598 | PKS | polyketide synthase, Streptomyces rapamycinicus, AGP57755 | 58/69 |
TPA0598_03_00750 | 7,054 | PKS | Beta-ketoacyl synthase, Streptomyces violaceusniger, AEM87320 | 57/68 |
TPA0598_03_00760 | 3,548 | PKS | Beta-ketoacyl synthase, Streptomyces violaceusniger, AEM87320 | 56/67 |
TPA0598_03_00770 | 1,846 | PKS | Beta-ketoacyl synthase, Streptomyces iranensis, CDR09758 | 62/73 |
TPA0598_03_00780 | 5,648 | PKS | polyketide synthase type I, Streptomyces aizunensis, AAX98191 | 58/69 |
TPA0598_03_00790 | 3,662 | PKS | hypothetical protein, Streptomyces sp. FxanaC1, WP_018091594 | 94/96 |
TPA0598_03_00800 | 3,265 | PKS | polyketide synthase, Streptomyces sp. PRh5, EXU66032 | 54/66 |
TPA0598_03_00810 | 270 | unknown | hypothetical protein, Streptomyces sp. FxanaC1, WP_018091596 | 95/96 |
TPA0598_03_00820 | 1,031 | NRPS | hypothetical protein, Streptomyces sp. FxanaC1, WP_018091598 | 94/96 |
TPA0598_03_00830 | 300 | unknown | hypothetical protein, Streptomyces sp. FxanaC1, WP_018091598 | 96/98 |
TPA0598_03_00840 | 1,923 | PKS | hypothetical protein, Streptomyces sp. FxanaC1, WP_018091599 | 91/94 |
TPA0598_03_00850a | 429 | cytochrome P450 | cytochrome P450, Streptomyces sp. FxanaC1, WP_026169967 | 92/96 |
TPA0598_03_00860 | 260 | unknown | membrane protein, Saccharopolyspora rectivirgula, KEI45939 | 45/69 |
TPA0598_03_00870 | 253 | type-II thioesterase | hypothetical protein, Streptomyces sp. FxanaC1, WP_018091603 | 95/97 |
TPA0598_03_00880a | 551 | amine oxidase | amine oxidase, Streptomyces sp. FxanaC1, WP_026169968 | 96/98 |
TPA0598_03_00890 | 344 | transcriptional regulator | hypothetical protein, Streptomyces sp. FxanaC1, WP_018091605 | 96/97 |
TPA0598_03_00900a | 496 | amidase | hypothetical protein, Streptomyces sp. FxanaC1, WP_018091606 | 94/95 |