Figure 9.

(A) Propionate and (B) butyrate degradation pathways in D. gibsoniae based on genomic data. The two main gene clusters for propionate and butyrate degradation are indicated in red and blue colors. For butyrate degradation, additional gene clusters were found, shown in different colors. For the other steps in the propionate degradation pathway, genes were found to be located in different places in the genome. Abbreviations: PCT, propionate CoA transferase; MCE, methylmalonyl-CoA epimerase; MCM, methylmalonyl-CoA mutase; SCS, succinyl-CoA synthase; SDH, succinate dehydrogenase; FHT, fumarase (fumarate hydratase); MDH, malate dehydrogenase; ODC, oxaloacetate decarboxylase; PFO, pyruvate:ferredoxin oxidoreductase; PFL, pyruvate formate lyase; POT, propionyl-CoA:oxaloacetate transcarboxylase; BAT, butyryl-CoA:acetate-CoA transferase; ACD, acyl-CoA dehydrogenase; ECH, enoyl-CoA hydratase; 3-HCD, 3-hydroxybutyryl-CoA dehydrogenase; ACA, acetyl-CoA acetyltransferase.