Table 6. Number of genes not found in near-relatives associated with the 25 general COG functional categories*

-

151

Hypothetical (no conserved gene family)

-

17

Transposase / Integrase (annotation-based)

-

80

Transport (annotation-based)

-

66

Signaling and Regulation

J

6

Translation

A

0

RNA processing and modification

K

51

Transcription

L

18

Replication, recombination and repair

B

0

Chromatin structure and dynamics

D

2

Cell cycle control, mitosis and meiosis

Y

0

Nuclear structure

V

7

Defense mechanisms

T

30

Signal transduction mechanisms

M

41

Cell wall/membrane biogenesis

N

20

Cell motility

Z

0

Cytoskeleton

W

1

Extracellular structures

U

22

Intracellular trafficking and secretion

O

9

Posttranslational modification, protein turnover, chaperones

C

20

Energy production and conversion

G

68

Carbohydrate transport and metabolism

E

28

Amino acid transport and metabolism

F

5

Nucleotide transport and metabolism

H

5

Coenzyme transport and metabolism

I

14

Lipid transport and metabolism

P

23

Inorganic ion transport and metabolism

Q

8

Secondary metabolites biosynthesis, transport and catabolism

R

43

General function prediction only

S

23

Function unknown

-

255

Not in COGs