Fig. 4
From: The microbiome and resistome of apple fruits alter in the post-harvest period
Distribution of drug-specific ARGs in fresh and stored apples. Only ARGs with at least 80% similarity and an e-value of 10–11 to reference ARGs are included and ARGs conferring multidrug resistance via efflux pumps, were excluded as they represented 57% of all ARG hits. A Circular representation of drug classes based on target-specific resistance gene abundances (right part of the circle) detected in fresh and stored Braeburn and Royal Gala apples (left part of the circle); thickness of ribbons refers to abundance of specific ARGs in the rarefied dataset. Visualization was generated using default settings of Circos software. B More detailed classification of the data shown in A, where each drug class is visualized in a separate panel. Y-axis of each panel represents total abundance of target-specific ARGs (note the different scaling) within apple samples that are represented on x-axis (I: BR fresh, II: BR stored, III: RG fresh, IV: RG stored). Stacked bars depict ARGs associated to the same antibiotic class within each sample; color-code for ARGs is shown on the right of each panel. Black arrows point to antibiotic classes to which resistance gene abundance is either increased or decreased in both stored apples compared to their fresh equivalents