Insights from the draft genome into the pathogenicity of a clinical isolate of Elizabethkingia meningoseptica Em3

Chen, Shicheng; Soehnlen, Marty; Downes, Frances P.; Walker, Edward D.

doi:10.1186/s40793-017-0269-8

Environmental Microbiome

Table 6 Antibiotic genes prediction

From: Insights from the draft genome into the pathogenicity of a clinical isolate of Elizabethkingia meningoseptica Em3

			E. meningoseptica		E. anophelis		E. miricola
Locus number	Gene in Em3	Putative function	Em3	502	R26	NUHP1	ATCC 33958	EM_CHUV
		β-lactam
BFF93_RS01220	bla _GOB-13	Class B carbapenemase Bla_GOB-13	+	+	+	+	+	+
BFF93_RS04805	–	β-lactamase	+	+	+	+	+	+
BFF93_RS05700	–	β-lactamase (EC 3.5.2.6)	+	+	+	+	+	+
BFF93_RS07625	bla _ACME	β-lactamase (Bla_ACME) VEB-1-like	+	+	+	+	+	+
BFF93_RS06860	bla _B	BJP β-lactamase	+	+	+	+	+	+
BFF93_RS09265	–	MBL fold metallo-hydrolase	+	+	+	+	+	+
BFF93_RS06995	–	β-lactamase (EC 3.5.2.6)	+	+	+	+	+	+
BFF93_RS14540	–	β-lactamase	+	+	+	+	–	+
BFF93_RS12085	–	β-lactamase (EC 3.5.2.6)	+	+	+	+	+	+
BFF93_RS12510	–	MBL fold metallo-hydrolase	+	+	+	+	+	+
BFF93_RS14000	blaB-9	Class B carbapenemase BlaB-9	+	+	+	+	+	+
BFF93_RS01365	–	β-lactamase (EC 3.5.2.6)	+	+	+	+	+	+
		Sulfonamide
BFF93_RS00125	dhfR	Dihydrofolate reductase DHFR	+	+	+	+	+	+
BFF93_RS17395	–	Bifunctional deaminase-reductase	+	+	+	+	+	+
BFF93_RS00125	dhfR	Dihydrofolate reductase DHFR	+	+	+	+	+	+
BFF93_RS17395	–	Bifunctional deaminase-reductase protein	+	+	+	+	+	+
BFF93_RS14765	folP	Dihydropteroate synthase FolP (EC 2.5.1.15)	+	+	+	+	+	+
		Tetracycline
BFF93_RS08380	tetA	Tetracycline efflux protein TetA	+	+	+	+	+	+
BFF93_RS07335	–	Transmembrane efflux protein	+	+	+	+	+	+
BFF93_RS12745	–	Antibiotic transporter	+	+	+	+	+	+
		Macrolide
BFF93_RS00370	lolD	Macrolide resistance, ABC transporter	+	+	+	+	+	+
BFF93_RS05670	emrB	Erythromycin resistance, EmrB/QacA	+	+	–	–	+	+
BFF93_RS05670	emrB	Erythromycin resistance, EmrB/QacA	+	+	+	+	+	+
BFF93_RS10830	emrB	Erythromycin resistance, EmrB/QacA	+	+	+	+	+	+
BFF93_RS03320	–	Erythromycin esterase	+	+	+	+	+	+
		Quinolone
BFF93_RS04670	gyrA	DNA gyrase GyrA subunit A (T83S)	+	+	+	+	+	+
BFF93_RS09245	gyrB	DNA gyrase GyrB subunit A (M437 L)	+	+	+	+	+	+
BFF93_RS08895	parE	DNA topoisomerase IV subunit B (M437F/A473L)	+	+	+	+	+	+
		Aminoglycoside
BFF93_RS10790	ant-6	Aminoglycoside 6-adenylyltransferase	+	+	+	+	+	+
		Chloramphenicol
BFF93_RS14765	catB	Chloramphenicol acetyltransferase CatB	+	+	+	+	+	+
BFF93_RS04080	bcr/cflA	Bcr/CflA efflux pump	+	+	+	+	+	+

“+” or “-” indicates the presence or absence of genes in the selected Elizabethkingia

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ISSN: 2524-6372

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