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Table 6 ORFs in the rakicidin-biosynthetic gene cluster of Streptomyces sp. MWW064

From: Draft genome sequence of Streptomyces sp. MWW064 for elucidating the rakicidin biosynthetic pathway

ORF (locus tag)

Size (aa)

Deduced function

Protein homolog [origin]

Identity/similarity (%)

Accession number

SSP35_09_01970

243

unknown

hypothetical protein [Streptomyces natalensis]

63/73

WP_030067339

SSP35_09_01960

331

transcriptional regulator

hypothetical protein DT87_01625 [Streptomyces sp. NTK 937]

59/69

KDQ65969

SSP35_09_01950

358

3-oxoacyl-ACP synthase

3-oxoacyl-ACP synthase [Streptomyces sp. NRRL S-920]

77/87

WP_030791445

SSP35_09_01940

79

ACP

phosphopantetheine-binding protein [Streptomyces bingchenggensis BCW-1]

68/79

ADI05068

SSP35_09_01930

406

ketosynthase

3-oxoacyl-ACP synthase [Streptomyces sp. NRRL S-15]

81/89

WP_031089521

SSP35_09_01920

146

unknown

methylmalonyl-CoA epimerase [Salinispora pacifica]

80/87

WP_018222873

SSP35_09_01910 (RakAB)

2,902

PKS

hypothetical protein [Streptomyces vitaminophilus]

63/73

WP_018385948

SSP35_09_01900 (RakC)

1,624

PKS

non-ribosomal peptide synthetase [Micromonospora sp. M42]

60/70

EWM63000

SSP35_09_01890 (RakD)

1,126

NRPS

hypothetical protein [Streptomyces vitaminophilus]

68/78

WP_018385946

SSP35_09_01880 (RakEF)

1,950

PKS

hypothetical protein [Streptomyces vitaminophilus]

64/73

WP_018385945

SSP35_09_01870 (RakG)

1,556

NRPS

hypothetical protein, partial [Micromonospora purpureochromogenes]

64/74

WP_030498976

SSP35_09_01860 (RakH)

1,565

NRPS

amino acid adenylation domain protein [Nostoc punctiforme PCC 73102]

38/55

ACC80782

SSP35_09_01850

563

ABC transporter

hypothetical protein [Micromonospora purpureochromogenes]

62/73

WP_030498978

SSP35_09_01840 (RakL)

251

type-II thioesterase

hypothetical protein [Streptomyces vitaminophilus]

64/73

WP_018385940

SSP35_09_01830 (RakN)

1,013

NRPS

non-ribosomal peptide synthetase [Micromonospora sp. M42]

55/63

EWM63010

SSP35_09_01820 (RakO)

331

asparagine oxygenase

clavaminate synthase [Streptomyces sp. LaPpAH-202]

64/75

WP_026235187

SSP35_09_01810

809

unknown

penicillin amidase [Amycolatopsis nigrescens]

63/74

WP_026359955

SSP35_09_01800

205

transcriptional regulator

putative LuxR family transcriptional regulator [Streptomyces glaucescens]

71/81

AIR96926

  1. SSP35_09_01910, SSP35_09_01900, SSP35_09_01890, SSP35_09_01880, SSP35_09_01870, SSP35_09_01860, SSP35_09_01840, SSP35_09_01830, and SSP35_09_01820 are corresponding to RakA plus RakB (RakAB), RakC, RakD, RakE plus RakF (RakEF), RakG, RakH, RakL, RakN, and RakO, previously reported in the reference [8], respectively, and SSP35_09_01940 may possibly be corresponding to RakI