Table 5 Modular PKS and NRPS gene clusters in Streptomyces sp. MWW064
From: Draft genome sequence of Streptomyces sp. MWW064 for elucidating the rakicidin biosynthetic pathway
Gene cluster | Encoded in | No. of modular PKS and NRPS genes | No. of modules | Backbone of predicted product |
|---|---|---|---|---|
pks/nrps-1 (rak) | scaffold 9 | 6 | 7 | R-C3-C3-Ser-C2-Gly-X |
pks/nrps-2 | scaffold 5 | 6 | 14 | C2-C2-C2-C2-C2-Gly-C2-C2-C2-C2-C2-C2-C2-C2 |
pks/nrps-3 | scaffold 2 | 4 | 3 | C?-C?-X |
pks/nrps-4 | scaffold 11 | 1 | 2 | X-C2 |
pks-1 | scaffold 18 | 5 | 5 | C?-C3-C2-C2-C? |
pks-2 | scaffold 23 | 1 | 1 | C? |
other pks a | scaffolds 11, 39, 45 | >3 | >10 | C2-C2-C3-C2, C2-C2, C2-C2-C2, C2 |
nrps-1 | scaffold 11 | 4 | 4 | X-X-Val-X |
nrps-2 | scaffold 18 | 3 | 3 | R-Val-X |
nrps-3 | scaffold 9 | 2 | 3 | R-Cys-mCys |
nrps-4 | scaffold 13 | 3 | 4 | Val-Gly-Ser-Pro |
nrps-5 | scaffold 2 | 1 | 1 | Ser |
nrps-6 | scaffold 12 | 1 | 1 | Thr |
other nrps a | scaffolds 3, 5 | >2 | >6 | X-X-X-X-X, Cys |